Iranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Investigation of The Corrosion Inhibitory Ability of Urena Lobata Leaves Extract on Mild Steel in Basic Media22524171347210.22034/ijnc.2024.2028701.1396ENNgozi JaneMaduelosiDepartment Of Chemistry, Rivers State University0000-0003-3473-3678Zorbari KelvinBarinekaChemistry, Science, Rivers State University, Port Harcourt, NigeriaNkemIrohaChemistry, Science, Federal University, Otuoke, Bayelsa.Journal Article20240527The Corrosion Inhibitive effectiveness of Urena lobata leaves extract on mild steel in 1M NaOH solution was investigated via gravimetric, Electrochemical and Surface analyses. Adsorption isotherms were investigated using the Langmuir and Freundlich plots. Gas Chromatography-Mass Spectrometric (GC-MS) technique was used for phytochemical screening. The protective effect of the leaves extract through immersion time, temperature and concentration were obtained. The results showed increasing inhibition efficiency with corresponding increase in extract’s concentration and protection was more at lower temperature. Using 2.5g/L of extract concentration, maximum inhibition efficiency of 100% was recorded. The corrosion rate increased with corresponding increase temperature in the basic medium. The adsorption process reduced as temperature increased thereby indicating physisorption. Chemisorption was detected since the Langmuir isotherms gave the best fit and observations from inhibition efficiency with varying temperature, activation energy and enthalpy of adsorption values confirmed physisorption thereby indicating extracts’ mixed properties. The inhibition efficiencies (% IE) were attributed to the phytochemical components (alkaloids, saponins, flavonoids, tannins, cynagenic glycosides) present in the extract. Urena lobata is an effective corrosion inhibitor of mild steel.https://www.ijnc.ir/article_713472_f6d8324d3c24415612e3cd28e730f26e.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Green Synthesis of Copper Nanoparticles Utilizing Pomegranate leaves Extract and Its Antibacterial Activity24225270489310.22034/ijnc.2023.2000750.1336ENMohmmad RezaAbdollahzadehQom university of technologyMohammad HadiMeshkatalsadatQom university of technology0000-0002-0009-6132Journal Article20230424In this report, a simple and eco-friendly biosynthesis of copper nanoparticles using Pomegranate leaves extracts as the reducing agent from CuNPs had been investigated. The formation of copper nanoparticles was characterized by UV-Vis spectrum, Fourier Transform Infrared Spectroscopy (FT-IR), and Scanning Electron Microscopic (SEM) analysis. The UV-Vis spectra results show a strong resonance centered on the surface of silver nanoparticles (CuNPs) at 280 nm. The Fourier Transformation Infrared Spectroscopy spectral study demonstrates Pomegranate leaves extract acted as the reducing agent. The scanning electron microscopic (SEM) analysis shows nanoparticles with an average particle size ranges about 19.82-38.15 nm. The structural characterization was carried out using XRD consistent with (111), (200), (311), and (400) reflections of the face-centered cubic (fcc) phase of the CuNPs .The biologically synthesized copper nanoparticles were found to be effective in controlling the growth of human pathogens viz., Salmonella. This route is rapid, simple, without any hazardous chemicals as reducing or stabilizing agents, and economical to synthesize CuNPs.https://www.ijnc.ir/article_704893_d93548179a6397a90506a969a11ce37e.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Comparative study of in-vitro antidiabetic property in the methanol extract of stem bark and leaves of Semecarpus anacardium Linn (Bhalayo) from Nawalparasi district, Nepal25326371377510.22034/ijnc.2024.2030765.1397ENBishan DattBhattTri-Chandra Multiple Campus, Tribhuvan University, NepalJournal Article20240531Semecarpus anacardium Linn (Bhalayo) has been used traditionally for ages as it can cure and control several incredible diseases including diabetes mellitus. In the present work, an investigation has been carried out to compare the in-vitro antidiabetic activity in the methanol extract of stem bark and leaves of Semecarpus anacardium Linn (Bhalayo) from Nawalparasi district of Nepal. Results from phytochemical screening in methanol (MeOH) extracts of stem bark and leaves of this plant discovered secondary metabolites like alkaloids, flavonoids, polyphenols and terpenoids. This demonstrates antioxidant and antidiabetic property with several other medicinal values of this plant. The in-vitro α-amylase enzyme inhibition activity of MeOH extract of either part of this plant was performed using starch as substrate, α amylase as enzyme, and acarbose as standard. The IC50 values of MeOH extract of stem bark and leaves were observed to be 88.26 ± 1.15 µg/mL and 195.61 ± 1.74 µg/mL, respectively. Nevertheless, the IC50 value of MeOH extract of stem bark, analogous to MeOH extract of leaves, seems fairly close to IC50 value of standard drug acarbose, 28.48 ± 0.07 µg/mL. Since, MeOH extract of stem bark of the plant unveiled its potent antidiabetic activity, stem bark of the plants can be employed for the isolation of active compounds to contrive new and efficacious antidiabetic drugs.https://www.ijnc.ir/article_713775_1a056833f1bfc6c4525f5915f6cfb963.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Hydrogels Based on Gum Arabic and Potassium Alum26428271232110.22034/ijnc.2024.2025294.1385ENFateh BelkasemEltaboniChemistry Department Faculty of Science University of Benghazi0000-0002-4539-6833Journal Article20240321Because of its tunable physical and chemical properties, bio-polymeric hydrogels have attracted increasing attention in biomaterials research because they can be used as sustainable and bioactive matrix in many applications such as drug release and dye recovery. Three formulations of hydrogels (F1, F2 and F3) based gum Arabic (GA) with different content of potassium alum (PA) (0.0, 0.002 and 0.200 grams of PA, respectively) were prepared by using solution-casting technique. A combination of spectroscopic (UV & FTIR) and hygroscopic techniques were applied to investigate the effect of PA content on the physicochemical properties of prepared hydrogels. FTIR spectra confirmed that hydrogels were successfully blended. It was noted that with increasing content of alum the moisture and gel contents increased, while swelling ratio decreased specially at pH 11. The highest value of mechanical parameter (elongation) was determined for the hydrogel containing the maximum amount of PA, i.e. F3 (1202 %). Thus, it could be concluded that for this system the highest crosslinking density has been achieved.https://www.ijnc.ir/article_712321_1abf07265eef2856a0aea342fe48acf9.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301An overview on recent trends of spinel ferrites (MFe2O4: M= Fe2+, Co2+, Mn2+, Ni2+, Zn2+) synthesis and catalytic applications28331771390710.22034/ijnc.2024.2032437.1398ENVidyaSinghMaharana Pratap
Govt
P G College0009-0006-9679-7166Journal Article20240614The synthesis of efficient catalysts is a key strategy for addressing the environmental and energy problems. Catalytic research has focused a lot of interest on spinel ferrites, which have a chemical formula of MFe2O4 (M = Fe2+, Co2+, Mn2+, Ni2+, Zn2+ etc). A multitude of surface-active sites, high catalytic activity and ease of modification are only a few of the many physicochemical characteristics of spinel ferrites, which are caused by the metal cations changeable location and valence flexibility. Meanwhile, their special benefits in recycling and regeneration because of their magnetic characteristics promote their practical use potential. This article examines how spinel ferrites are made utilizing conventional and environmentally friendly chemical processes. Most significantly, a thorough review of the major pathways, mostly connected to selective doping, site replacement, structural reversal, defect introduction and linked composites is provided in order to enhance catalytic performance. A review is also given to the many catalytic uses of spinel ferrites and the composites they produce, such as Fenton-type catalysis, photocatalysis, electrocatalysis, and photo-electro-chemical catalysis. Important factors including recovery, reuse, and toxicity are also addressed. It is anticipated that spinel ferrites will be utilized in energy and environmental applications in the future. These applications will be driven by the development of expert modification, accurate synthesis, complex characterization, and theoretical calculations.https://www.ijnc.ir/article_713907_b1f1b17aeee70f2e3a8a5f1be9185483.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Thermodynamic analysis for the dissolution of Pimelic acid in water + ethanol binary mixture at T = 305.18 - 313.15K31832870912510.22034/ijnc.2023.2009938.1357ENSandip BNahireM.P.H.Mahila Mahavidyalaya, Malegaon Camp, Dist. Nashik, Maharashtra, IndiaJournal Article20230825This study concentrated on numerical calculations and experimental observations of pimelic acid solubility in water, ethanol, and their binary mixtures. The solubility of pimelic acid in pure solvents and their binary mixes was determined using the equilibrium measurement method at temperatures (305.15 - 313.15) K. The experimental findings were correlated to the Apelblat equation in order to evaluate the data quality. The solubility correlations predicted by the Apelblat model agreed well with the results of the experiments. <br /><br />1,7-Heptanediol, a crucial molecule utilized in the creation of drugs, surfactants, fragrances, and cosmetics, is produced using pimelic acid as a starting material. These investigations examined the solubilities of pimelic acid in pure water, ethanol, and their binary mixes throughout a range of compositions at various temperatures. The experimental solubility data were correlated using the Apelblat model. Using the van't Hoff equation, the thermodynamic characteristics of the solutions were calculated. Ethanol seems to have a higher solubility than water, according to measurements.https://www.ijnc.ir/article_709125_5d8129ecdde16484d6eb6d8870b47edd.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Preparation and Characterization of Pd/CuFe2O4 magnetic nanocatalyst and their application in Sonogashira cross-coupling reaction32933970922410.22034/ijnc.2023.2012885.1366ENRITUPARNACHUTIAGUWAHATI COLLEGEBOLINCHETIADIBRUGARH UNIVERSITYJournal Article20231117Herein we report the biogenic synthesis of Pd/CuFe2O4 magnetic nanocatalyst using Lantana camara flowers for the Sonogashira cross-coupling reaction. The as-prepared magnetic nanoparticles have been extensively characterized by powder X-ray diffraction (PXRD), SEM, EDX, TEM, HRTEM, ICP and BET surface area measurement techniques. The activity of different catalyst such as CuFe2O4, Pd/NiFe2O4 and Pd/Fe3O4 were investigated for Sonogashira cross-coupling reaction and it was observed that Pd/CuFe2O4 showed superior catalytic activity compared to the other catalyst systems. The use of non-toxic commercially available solvents, mild reaction conditions, easy preparation of the catalyst, high yield of the products and less reaction time are the advantages of the present protocol. The catalyst showed higher selectivity towards coupling of aryl halides with alkynes resulting in moderate to excellent isolated yields. The catalyst was easily separated with the help of an external magnet and reused upto 5th cycle without any significant loss in the catalytic activity and product yield.https://www.ijnc.ir/article_709224_5152877e3ba82bd19715194e6fe59e1c.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Surface Water Quality and Health Risk Assessment of Some Potentially Toxic Metals in Ogun River, Nigeria34036771721310.22034/ijnc.2024.2044091.1419ENCHRISTIAN CHINWEUBAONOYIMADEPARTMENT OF CHEMISTRY, NIGERIA POLICE ACADEMY, WUDIL, NIGERIA0009-0005-8765-4684Olalekan BabatundeAdesinaNational Research Institute for Chemical Technology, Zaria, NigeriaElaoyi DavidPaulDepartment of Chemistry, Ahmadu Bello University, Zaria, NigeriaFriday GodwinOkibeDepartment of Chemistry, Federal University of Health Sciences, Otukpo, NigeriaJournal Article20241023Freshwater resources face global threats from anthropogenic pollution, posing human health and ecological risks. The water quality of Ogun River was assessed using the Weighted Arithmetic Water Quality Index (WWQI), The Canadian Water Quality Index (CWQI), the Heavy Metals Pollution Index (HPI), and the Comprehensive Pollution Index (CPI); the Carcinogenic and Non-Carcinogenic risk assessment of some toxic metals through oral and dermal exposures was carried out. The heavy metals were measured with the Microwave Plasma Atomic Emission Spectrometer (MP-AES). The results from all the evaluation indices show that the River is highly polluted at all sampling stations and in all seasons. WWQI and HPI show that the water quality decreased from the dry to the rainy season due to a rise in heavy metal levels. At the same time, WQI indicates that the level of the physicochemical parameters decreased from the dry to the rainy season. Cd and Pb posed significant non-carcinogenic risk (HQ > 1) through oral exposure to adult and children populations at all locations, accounting for 98.27 % of the total risk. There was a significant cancer risk (CR >110-4) through oral exposure to Pb and Cr for the adult populations at 31.25 % and 62.50 % of the sampling locations respectively, while oral and dermal exposure to Cd posed a significant cancer risk for the adult and children populations at all the sampling locations. The river's water quality is impacted mainly by heavy metals, which pose significant human health risks.https://www.ijnc.ir/article_717213_560861f3fc65395fb2527a6f84fafc72.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Evaluating the Performance of Red Onion Skin Extract in 0.2M Hydrochloric Acid as a Green Corrosion Inhibitor for Aluminum36838371196610.22034/ijnc.2024.2022275.1374ENThomas AondofaNyijimeJoseph Sarwuan Tarka University, Makurdi0000-0001-9537-1987Journal Article20240205The inhibition effect of red onion ethanol extract on the corrosion of aluminium in 0.2M aqueous HCl solution at 303, 313 and 323 K was investigated by weight loss method. The results showed that the inhibition efficiency decreased with temperature rise but increased with the inhibitor concentration from 0.2 to 0.8g/L. The highest inhibition efficiency of weight loss was 80.00% and the lowest was 63.0% as the temperature of the system increased. The activation energy (Ea) for Red onion ethanol extracts values for the blanks in 0.2M HCl were high compared to the values obtained when the extract was introduced into the system at 0.2 to 0.8g/L respectively. Langmuir isotherm provided more accurate description of the adsorption behavior of red onion peel with the R2 values closer to unity. The thermodynamic parameters Kads, ΔHads and ΔSads were determined. The extract of red onion peel increased the life-span of the aluminium hence the half-life of blank was relatively lesser when compared to that immersed in plant extract. Surface characterization methods including FT-IR were used to ascertain whether the plant extract interacted with the aluminium surface, and it was found that the mode of interaction was adsorptive in nature. It could be concluded that the ethanol extract of red onion peel inhibits aluminium in hydrochloric acid solution.https://www.ijnc.ir/article_711966_a9b38e292d871dcb7b3be592a8af402f.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Facile Characterization and Quantification of Total Petroleum Hydrocarbon and Polycyclic Aromatic Hydrocarbons in Water and Sediment Samples from Three Creeks in Bonny L.G.A of Rivers State, Nigeria38440071305810.22034/ijnc.2024.2026649.1387ENChidiObiUniversity of Port HarcourtIhechiNwankpaDepartment of Pure and Industrial Chemistry, Faculty of Science, University of Port Harcourt, Rivers State, NigeriaGloria U.ObuzorDepartment of Pure and Industrial Chemistry, Faculty of Science, University of Port Harcourt, Rivers State, NigeriaJournal Article20240416The exploration and exploitation of crude oil in Niger Delta has resulted in continued oil spillage into the water bodies and the land around the region. Hence, this study focuses on the evaluation of the amount and types of Polycyclic Aromatic Hydrocarbons (PAHs) and Total Petroleum Hydrocarbons (TPH) in the water and sediment samples of three Creeks namely Fibiri, Adamkiri, and Okpokoma Dappa in Bonny Local Government Area of Rivers State using Gas Chromatography-Flame Ionization Detector (GC-FID). The results obtained revealed variations in the concentrations of PAHs and TPH within the sediment and water samples extracted from these three locations. Fibiri Creek emerged as the focal point of heightened 16-priority PAH levels studied, succeeded by Adamikiri and Okpokoma Dappa Creeks. Similarly, the concentration of TPH in water samples mirrors the decreasing order across the three Creeks as Fibiri > Adamakiri > Okpokoma Dappa. In Fibiri Creek, n-C32 commands the highest concentration at 11.3224 ppm, while Okpokoma Dappa manifests the lowest concentration with n-C11 registering at 1.19456 e-2 ppm. This study exposed that Low Molecular Weight (LMW) PAHs such as naphthalene, acenaphthylene, acenaphthene, fluorene, and anthracene were predominant underscoring the pervasive influence of petroleum-related activities. However, High Molecular Weight (HMW) PAHs like Dibenzo [a, h] anthracene was also discernible contributing to the complex PAH profile observed across the studied Creeks. This research provides a good knowledge of hydrocarbon matrices across the three Creeks, offering a foundation for targeted environmental management strategies and remediation efforts.https://www.ijnc.ir/article_713058_e00e56a2722844e4d0e61733e8953f7d.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301An Update Review on the Developed Chromatographic Methods for the Analysis of Tricyclic Antidepressants40141071891110.22034/ijnc.2025.718911ENMahnazQomiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.Journal Article20241210<span style="font-size: 11.0pt; line-height: 150%; color: black;">This review paper provides a comprehensive update on the advancements in chromatographic methods for the analysis of tricyclic antidepressants (TCAs), a class of medications widely used in the treatment of depression and other mood disorders. The paper discusses the evolution of chromatographic techniques, including gas chromatography (GC), high-performance liquid chromatography (HPLC), and ultra-performance liquid chromatography (UPLC), highlighting their respective advantages and limitations in the context of TCA analysis. Recent innovations such as the incorporation of mass spectrometry (MS) for enhanced sensitivity and specificity are also explored. The review further examines sample preparation methodologies, including solid-phase extraction (SPE) and liquid-liquid extraction (LLE), which play a critical role in achieving accurate quantification and detection. Additionally, the paper addresses the challenges associated with the complex matrix of biological samples, such as plasma and urine, and evaluates strategies for overcoming these obstacles. By synthesizing current research findings, this review aims to provide insights into the optimal selection and application of chromatographic techniques for TCA analysis, thereby supporting clinical and forensic investigations.</span>https://www.ijnc.ir/article_718911_17b1371b87cd6b6a791c7253348bde98.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Structural and Chemical Study of the Effect of Doping the Pyridine Ring on the Structure of Boron-carbon-nitrogen (BCN) Nanotubes in two Configurations: Armchair (3,3) and Zigzag (6,0)41142471894610.22034/ijnc.2025.718946ENKianooshSakinezhadDepartment of Chemistry, Dezful Branch, Islamic Azad University, Dezful, IranHalimehRajabzadehDepartment of Chemistry, Dezful Branch, Islamic Azad University, Dezful, IranZhilaSafariDepartment of Chemistry, Dezful Branch, Islamic Azad University, Dezful, IranJournal Article20241211The synthesis processes of nanomaterials have been rapidly growing and have made it possible to <br />achieve new materials such as heterogeneous structures that exhibit new and attractive phenomena and <br />physical properties. To achieve desirable properties, it is necessary to chemically modify these materials. <br />In this research, the structural and chemical properties of armchair and zigzag carbon nanotubes and <br />boron-carbon-nitrogen (BCN) composite nanotubes were first examined, and the changes in the <br />structural and chemical properties of the boron-carbon-nitrogen (BCN) composite nanotubes due to the <br />addition of pyridine were studied. The initial structure of the compounds was drawn using ChemOffice <br />software. The optimization of the structures and the calculation of parameters were performed in <br />Gaussian 09 based on density functional theory calculations at the B3LYP/3-21G theoretical level. The <br />results showed that boron-carbon-nitrogen composite nanotubes are more stable than carbon nanotubes, <br />and doping with pyridine resulted in greater stability of the pyridine-doped composite nanotubes. Zigzag <br />nanotubes are slightly more stable than armchair ones. This study shows that the stability, activity, and <br />reactivity of BCN composite nanotubes have changed with doping with pyridine and under the influence <br />of the structural changes made, and by altering the chemical and structural properties of BCN composite <br />nanotubes, their application in various electrical, chemical, and medical industries can be modified or <br />improved. https://www.ijnc.ir/article_718946_faecdc1ff9a276b5dbad0c21197cb300.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Evaluation of Antioxidant, Antimicrobial and Phytochemical outlook of Vitex doniana fruit extract42543970923610.22034/ijnc.2023.2015843.1365ENSamson AbahAbagaleBox 240000-0001-6158-2102ShakiraIbrahimDepartment of Applied Chemistry
Box 24
Navrongo, UERMoses A.AgbalaDepartment of Applied Chemistry
Box 24
Navrongo, UERDanielOduro-MensahWACCBIP, University of Ghana, LegonJacob K.DonkorWACCBIP, University of GhanaJournal Article20231116Vitex doniana is a multi-purpose tree found in Africa with a lot of benefits. Different parts of the tree have been put to various uses including medicinal and nutritional purposes. The tree is abundant in some West African countries including Ghana and its black colored fruit is eaten by indigenes. Evaluation of useful properties of the fruit is earmarked to generate data on its useful properties when consumed, otherwise also to drive its commercialization. In the current research, antioxidant, antimicrobial and phytochemical studies were carried out on the crude aqueous extracts of the fruit. The antioxidant potential was assessed through reducing/antioxidant power through ion chelation, DPPH total antioxidant capacity and hydrogen peroxide scavenging activity studies. Antimicrobial activity on B. spp, S. aureus and E. coli using the agar-disc diffusion method, and phytochemical screening were also carried out. In the antioxidant studies, the ferric reducing antioxidant power of the extract was from 55.60±2.2 - 80.77±04 %, the DPPH scavenging activity was in the range 32.47±1.6 - 49.51±5.9 % and the hydrogen peroxide reduction was in the range 20.46±1.8 - 28.84±0.8 %. At the concentrations tested, the extract had no visible antimicrobial activity on strains of Bacillus subtilis, Staphylococcus aureus and Escherichia coli used in the study. Among the eight phytochemicals screened in the extract, saponin, glycosides, alkaloids, tannins, phenolics and steroids were present in the extract. Toxicity studies are required to evaluate the biosafety of fruit for continuous consumption and also commercialisation.https://www.ijnc.ir/article_709236_7bb55df9698ce65dcdc82bf1a8f9bc52.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301A Review: Bismuth Oxy Halide Based Materials (BiOX: X= Cl, Br and I) Heterostructures Nanofiber’s and Photo Catalytic Activity44046071399810.22034/ijnc.2024.2033720.1401ENVidyaSinghMaharana Pratap
Govt
P G College0009-0006-9679-7166Journal Article20240625In recent times, there's been a surge in the popularity of bismuth-based materials, particularly BiOX (Bismuth oxy halides), owing to their distinct layer structure and suitable energy band gap. They find extensive applications in both environmental and energy sectors, making them a focal point of research lately. Various synthesis methods such as hydrothermal, solvothermal, hydrolysis, calcination, and ultrasound-assisted methods are employed for BiOX fabrication. This review delves into the synthetic approaches of BiOX-based heterojunctions, emphasizing the charge transfer pathways and photocatalytic mechanisms of different types of heterojunctions, including conventional type II, Z-scheme, p-n and S-scheme heterojunctions. These heterojunction designs play a pivotal role in accompanying figure. Additionally, the review provides insights into specific applications of BiOX-based heterojunction materials in energy and environmental fields. Regarding the stability of Bi3+, significant research has focused on compounds containing bismuth, such as BiOX with the Sillén structure (where X = Cl, Br, or I). However, to address the need for improved performance, modifications are necessary, particularly for compounds with broader band gaps. The chapter provides a comprehensive overview of heterojunction systems employed to augment the redox potential of BiOX photocatalysis, alongside an examination of existing challenges and future research avenues. The overarching aim is to expand the scope of research concerning BiOX-based materials while offering insights for future investigations. Additionally, the chapter underscores potential factors influencing the photocatalytic activity of BiOX-based heterojunctions, delineating both opportunities and challenges for further research and development.https://www.ijnc.ir/article_713998_09c5f88b7dd5db6217a1fc8017b652bf.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Chemical and Judgmental Examination of Niosomes or Vesicles of Non-Ionic Surfactants46147371908510.22034/ijnc.2022.552852.1271ENMoradSouri LakiMD Department of Microbiology, Islamic Azad University, Tehran North Branch, Tehran, IranFarzanehHosseiniDepartment of Microbiology, Islamic Azad University, Tehran North Branch Tehran, IranRobabRafiei TabatabaeiAssociate Professor, Department of Microbiology, Faculty of biological sciences, Islamic Azad University, North Tehran branch, IranJournal Article20220428Niosomes or vesicles of nonionic surfactants are very small layered structures obtained from a mixture of nonalionic surfactants of alkyl or diakyl polyglycerol ether and cholesterol and then hydration in aqueous (aqueous) medium. Today, overuse of antibiotics in the treatment of human and animal diseases has caused the multidrug resistance of bacteria to antibiotics. In addition, if a new type of antibiotic is used, resistance genes will begin to appear. After a period of widespread transmission to other bacteria, the spread of resistance and the need for new antibiotics, which requires millions of dollars. Vancomycin is used to treat infections of many gram-positive and gram-negative bacteria. Consumption of this antibiotic is very high due to the bacterial resistance that has been created against it as well as the side effects that it causes in some parts of the body. Many studies have been done on antibiotics to find a solution to eliminate the toxicity caused by their long-term use.https://www.ijnc.ir/article_719085_9964e9208cfc7a5e2a975bf256aca9e1.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Synthesis of (E)-3-(4-(dimethylamino)phenyl)-1-(2-hydroxy-5-((E)-o-tolyldiazenyl)phenyl)prop-2-en-1-one and (E)-2-(4-(dimethylamino) phenyl)-6-(o-tolyldiazenyl)-4H-chromen-4-one47448471347110.22034/ijnc.2024.2030043.1394ENHadi AKhderaTishreen University0000-0001-5361-8945Journal Article20240523A new azochalcone derivative (5) (E)-3-(4-(dimethylamino) phenyl) -1- (2-hydroxy -5- ((E) -o- tolyl diazenyl) phenyl) prop-2-en-1-one was synthesized through the reaction of diazotization and coupling of the aromatic amine 2- methyl aniline with the chalcone compound (E) -3- (4-(dimethylamino) phenyl) -1- (2-hydroxyphenyl)prop-2-en-1-one in the presence of sodium nitrite And hydrochloric acid. A new azoflavone derivative (6) (E) -2- (4-(dimethyl amino) phenyl)-6-(o-tolyl diazenyl) -4H- chromen -4- one was also synthesized with high yield through the cyclization reaction of the compound azo chalcone (5) using iodine in dimethyl sulfoxide (DMSO). The chemical structures of the two new compounds were confirmed by spectroscopic methods (13C-NMR, 1HNMR, FT-IR). The biological activity of the two compounds (5 , 6) was investigated at two different concentrations (0.5 mg/ml, 0.25 mg/ml) on three fungal species (Penicillium expansum, Acremonium strictum and Aspergillus flavus) and compared with clotrimazole as a standard antifungal. These compounds showed good activity against the tested fungi, and were most effective on the fungal species Acremonium strictum.https://www.ijnc.ir/article_713471_263689a789bf5dcce6e8b9876b7624a3.pdfIranian Chemical Science and Technologies AssociationInternational Journal of New Chemistry2645-723712320250301Optimization of Traditional Polyvinyl Acetate with Hydroxylated Guna Seed Oil as a Feasible Copolymer Binder48550170145610.22034/ijnc.2023.1986341.1320ENJoshua AGidigbiModibbo Adama University0000-0001-7981-4792Journal Article20221231The study sought to produce an emulsion paint binder that will compensate for inadequacy found in traditional polyvinyl acetate binder by optimizing with hydroxylated Guna seed oil (HGSO). Oil was extracted mechanically from Guna seed, and subjected to chemical process of epoxidation to open the carbon to carbon double bond ring for inclusion of hydroxyl group via hydroxylation process. The product-polyol was optimized by copolymerised the HGSO with polyvinyl acetate in series of blend to form a new copolymer binder. Fourier Transformation Infrared (FTIR) was used to assess the chemical change in the chemical processes. The novel PVAc /HGSO copolymer binder was optimised by introducing different concentration of HGSO into the copolymer matrix and examine the crucial paint binder parameters such as density, water solubility, refractive index, melting point, moisture absorptivity, gel time, viscosity, and turbidity. Comparing with permissible value in coating industry, the blend ratio 80: 20 (80% of PVAc and 20% of HGSO) was adopted for the formulation of PVAc/HGSO copolymer binder. The novel PVAc/HGSO copolymer binder resist water excellently with a good optical property and better adhesiveness. Therefore, the novel PVAc/HGSO copolymer binder can be used to formulate an emulsion paint.https://www.ijnc.ir/article_701456_ed178254f1530246bfc75d0d015007f3.pdf