Experience of using magnesium sulfate infusion in the operating room to induce analgesia after laparoscopic cholecystectomy

Document Type : Research Paper

Authors

1 Assistant Professor of Surgery, Department of General Surgery, Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2 Associate Professor of Anesthesiology, Department of Anesthesiology, Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

10.22034/ijnc.2022.4.7

Abstract

Introduction: The aim of the present study was the experience of using magnesium sulfate infusion in the operating room to induce analgesia after laparoscopic cholecystectomy.

Material and Methods: This study was conducted as a clinical experiment in 2018 with the participation of 40 patients who were candidates for laparoscopic cholecystectomy. Magnesium group (M) received 50 mg/kg of magnesium sulfate IV in 100 cc normal saline 0.9% and control group (C) 100 cc normal saline 0.9% after intubation. Intensity was then measured at different times. Pain intensity was measured and compared between the two groups in different situations.

Results: There was no statistically significant difference in changes in the amount of pain at rest between the two groups (p-value=0.925) and it can be said that the two drugs did not have different effects. Repeated measures were examined and it was found that the age variable did not have a statistically significant effect on changes in the amount of pain in cough (p-value=0.925).

Conclusion: Administration of magnesium sulfate at a dose of 50 mg/kg has no effect on pain intensity and dose of drug used after Laparoscopic cholecystectomy surgery and also changes systolic and diastolic blood pressure and arterial blood oxygen saturation percentage during and at the end of the operation.

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