The present study was performed with the aim of Comparison of headache severity before and after rhinosinusitis surgery in patients referred to clinics in Tabriz. This prospective descriptive study was performed with the participation of 47 patients with headache due to rhinosinusitis. All patients underwent medication due to severe headache and underwent surgery due to non-response to treatment. The severity of preoperative and postoperative headache in patients was assessed. Response to overall treatment was statistically significant (P=0.005). The overall success rate of pain reduction in our study was 83%, with a complete recovery rate of 11% and a significant reduction in symptoms of 72%. 17% of cases did not show a clear change. In the first group, only half of the cases had reduced symptoms (P=0.041). In the second group, 100% reduction of symptoms, in the third group, 93% results (86% reduction of symptoms and 7% complete recovery) and in the fourth group, 100% response to treatment (60% complete improvement and 40% reduction of symptoms) Was seen (P=0.005).