Thermodynamic-Biochemical Study of Complexes of Intermediate Elements with α-Amino Acids in Some Proteins with Active Site

Document Type : Research Paper

Author

Department of Chemistry, School of Engineering, Presidency University, Bengaluru-560064, India.

Abstract

In this paper, the quantum chemistry calculations related to the structural parameter of the chromite and molybdate anions and the complexes obtained from them with the glycine and alanine amino acids were performed. The calculations were carried out using HF and DFT methods and in the base series 6-31G *. Thermodynamic studies related to the formation of complexes have been considered and their equilibrium constant has been calculated. Finally, by comparing the thermodynamic factors, the stability of the complexes was determined relative to each other.

Keywords

References

[1] M. Outokesh, A. Tayyebi, A. Khanchi, F.Grayeli, G. Bagheri, J. Microencapsulation, 28(4), 248 (2011).
[2] J.G. Lambardino, E.H. Wiseman, J. Med.Chem., 17, 1182 (1974).
[3] A. Puratchikody,M. Doble, Bioorg. Med. Chem. Lett., 15, 1083 (2007).
[4] M. Antolini, A. Bozzoli, C. Ghiron, Bioorg.Med. Chem. Lett., 9, 1023 (1999).
[5] L. Wang, K.W. Woods, Q. Li, J. Med.Chem., 45, 1697 (2002).
[6]M. Y.Pathan,V. V. Paike, P. R.Pachmase, S.P.More,S. S. Ardhapure, R. P. Pawar, Arkivoc, Part (xv), 205 (2006).
[7] J.C. Lee, J.T. Laydon, P.C. McDonnell, Nature, 372, 739 (1994).
[8] T. Maier, R. Schmierer, K. Bauer, U. S. Patent 4820335 (1989); Chem. Abstr., 111, 19494 (1989).
[9] R. Schmierer, H. Mildenberger, H. Buerstell, German Patent 361464 (1987);
Chem. Abstr., 108, 37838 (1988).
[10] P. Wasserscheid, W. Keim, Angew. Chem.Int. Ed. Eng., 39, 37872 (2000).
[11] I. Satoru, Japn Kokkai Tokyo Koho JP 01, 117, 867, May 10, 1989; Chem. Abstr., 111, 214482 (1989).
[12] S. Samai, G.C. Nandi, P. Singh, Tetrahedron, 65, 10155 (2009).
[13] S.A.A. Mansour, K.U. Sadek, Chin. Chem. Lett., 20, 812 (2009).
International Journal of New Chemistry
Volume 4, Issue 2
Spring 2017
Pages 39-43

Files

Share

How to cite

Statistics