Pyridazinone Compounds: A Mini review on their antifungal activities

Document Type: Review

Authors

1 Department of Pharmacy, Himalayan Institute of Pharmacy and Research, Dehradun, (Uttarakhand), 248007, India

2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, India

Abstract

Pyridazine derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. They are widely used in pharmaceuticals and agrochemicals. In view of these facts and in continuation of our interest in the chemistry of pyridazines, pyridazinones are six membered cyclic 1,2-diazine having carbonyl group at 3-position of ring system. They are widely used for industrial purposes and also exhibit a broad range of biological activities. This short review compiles examples of the most promising antibacterial activity. An overview on the antifungal activity is also described.

Keywords


[1] Asif M, Singh A, Ratnakar L. J. Pharm. Res., 4, 664 (2011).
[2] Siddiqui AA, Ahamad SR, Mir MS, Hussain AS, Raish M, Kaur R. Acta. Pol. Pharm., 65, 223 (2008).
[3] Asif M, Singh A, Lakshmayya. Am J. Pharmacol. Sci., 2, 1 (2014).
[4] Asif M, Singh A, Lakshmayya. Iran. J. Pharm. Sci., 9, 67 (2013).
[5] Asif M, Singh A, Lakshmayya, Husain A, Siddiqui AA. Lett. Drug. Design. Discov., 10, 651 (2013).
[6] Asif M, Singh A, Lakshmayya. Chronicle. Young. Scientist., 4, 1 (2013).
[7] Asif M, Anita Singh A, Siddiqui AA. Med. Chem. Res., 21, 3336(2012).
[8] Asif M, Singh A. Int. J. Chem. Tech. Res., 2, 1112 (2010).
[9] Dogruer DS, Onkol T, Ozkan S, Ozgen S, Sahin MF. Turk. J. Chem., 32, 469 (2008).
[10] Zou, X.-J, Jin, G.-Y, Zhang, Z.-X. J. Agric. Food. Chem., 50, 1451 (2002).
[11] Zou, X.-J, Jin, G.-Y, Yang, Z. Chem. J. Chin. Univ., 23, 404 (2002).
[12] Zou, X.-J, Jin, G.-Y. Chin. Chem. Lett., 12, 419 (2001).
[13] Cramer, R. D, Pattern, D. E, Bunce, J. D. J. Am. Chem., Soc., 110, 5959(1988).
[14] Lamberth C, Trah S, Wendeborn S, Dumeunier R, Courbot M, Godwin J, Schneiter P. Bioorg. Med. Chem., 20, 2803 (2012).
[15]Walker SS, Xu Y, Triantafyllou I, Waldman MF, Mendrick C, Brown N, Mann P, Chau A, Patel R, Bauman N, Norris C, Antonacci B, Gurnani M, Cacciapuoti A, McNicholas PM, Wainhaus S, Herr RJ, Kuang R, Aslanian RG, Ting PC, Black TA. Antimicrob. Agents. Chemother., 55, 5099 (2011).
[16] Zhou G, Ting PC, Aslanian R, Cao J, Kim DW, Kuang R, Lee JF, Schwerdt J, Wu H, Herr RJ, Zych AJ, Yang J, Lam S, Wainhaus S, Black TA, McNicholas PM, Xu Y, Walker SS. Bioorg. Med. Chem. Lett., 21, 2890 (2011).
[17] Butnariu RM, Mangalagiu II. Bioorg. Med. Chem., 17, 2823 (2009).
[18] Wu J, Song B, Chen H, Bhadury P, Hu D. Molecules., 14, 3676 (2009).
[19] Islam M, Siddiqui AA, Rajesh R, Bakht A, Goyal S. Acta. Pol. Pharm,. 65, 441-4472008).
[20] Abdel-Hafez SH. Eur. J. Med. Chem., 43, 1971 (2008).
[21] Zou, X.-J, Jin, G.-Y. Chin. J. Pestic. Sci., 3, 17(2001).
[22] Zou, X.-J, Jin, G.-Y, Yang, Z. Chin. J. Appl. Chem., 18, 599 (2001).
[23] Rogut O, Stefănescu E, Apreutesei A. Rev. Med. Chir. Soc. Med. Nat. Iasi., 107, 868 (2003).
[24] Zou X-J, Lai L-H, Jin G-Y, Zhang Z-X. J. Agric. Food. Chem., 50, 3757 (2002).
[25] Zou XJ, Jin GY. Chinese. Chem. Lett., 12, 419 (2001).
[26] Ungureanu M, Mangalagiu I, Grosu G, Petrovanu M. Ann. Pharm. Fr., 55, 69 (1997).
[27] Easmon J, Heinisch G, Holzer W, Matuszczak B. Arch. Pharm. (Weinheim)., 328, 307 (1995).
[28] Coburn RA, Carapellotti RA. J. Pharm. Sci., 65, 1505 (1976).
[29] Sonmez M, Berber I, Akbaş E. Eur. J. Med. Chem., 41, 101 (2006).
[30] Islam M, Siddiqui AA, Rajesh R. Acta. Pol. Pharm., 65, 353 (2008).