Document Type : Original
Authors
1 114 Gwangwazo
2 Department of chemistry Aliko dangote university of science and technology wudil
Abstract
Metal complexes of Co(II), Ni(II) and Zn(II) complexes of Schiff base derived from 2-aminothiophenol and 2-methoxyphenylacaetaldehyde have been synthesized and characterized by conductivity measurement, magnetic measurement and spectroscopic analysis. Infrared spectra of the Schiff base revealed azomethine peak at 1640 cm-1 . This band was shifted to higher or lower wave numbers in the complexes, indicating the participation of the azomethine nitrogen in coordination (M-N), also a new peak in the range of 717 – 786 cm-, the participation of the SH group in chelation is ascertained from the shift of the and υ(C-S) from 730 cm-1 and 758 cm−1 to lower or higher wave numbers in the spectra of the complexes. New bands at 780-750 cm-1, 660-700 cm-1 been assigned to υ(M-N) and υ(M-O) respectively. Conductance measurement (1.64 – 30.50 Ohm-1 cm2 mol-1) suggested the non-electrolytic nature of all the complexes. Magnetic susceptibility analysis of the complexes gave results in the range of 1.94 – 5.32 B.M. suggesting octahedral geometry for all the complexes. The metal ligand reacting ratio was confirmed by Jobs method of continuous variation. From the Job’s plot the number of coordinated ligand was determined which indicate a 1:2 metal ligand ratio for the metal complexes. The Schiff base and its metal chelates were screened for antimicrobial activity against six pathogenic microbes (Staphyloccus aureus, Escherichia coli Candida albican, and Mucor indicus), the Schiff base shows moderate activity, while the complexes show higher antimicrobial activity against the tested microbes.
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