ISC, DOAJ, CAS, Google Scholar......

Document Type : Original

Authors

1 Ghadr Institute of Higher Education, Department of Pharmaceutical Chemistry, Koochesfahan, Guilan.

2 Department of Chemistry, Faculty of Science, University of Guilan, P.O. Box 41335-1914, Rasht, Iran

3 Department of Engineering Science and, Faculty of Engineering, East Guilan, University of Guilan, P.O. Box: 41938-33697, Iran

4 Ghadr Institute of Higher Education, Department of Pharmaceutical Chemistry, Koochesfahan, Guilan

Abstract

Application of green chemistry for the synthesis of silver nanoparticles (AgNPs) using extracts of takes off of Ruta, Pimpinella saxifrage, and mango. And also a new method to reproduce new drugs based on silver nanoparticles with omeprazole and omeprazole sulfide and pantoprazole and pantoprazole sulfide with extricates of Ruta, Pimpinella saxifrage, and mango. In this investigation, the plant extricate was used to create natural silver nanoparticles. In this reaction, each drug was carried out with silver nitrate salt with a concentration of 30 ml at room temperature, which changes the color of the compound from green to dark. In expansion, within the second step, silver nanoparticles were included within the narcotic, and an advanced metal nanoparticle from the plant extricates as a silver molecule reducer. The retention crest esteem is between 400-450 nm for the extricate and the color alters to dark compared to silver plasmon retention. FT-IR range appeared that drugs were effectively put on the surface of silver nanoparticles.

Keywords

Main Subjects

  1. Benita, S., Microencapsulation: methods and industrial applications. 2005: Crc Press.
  2. Arias, J.L., Nanotechnology and drug delivery, volume one: nanoplatforms in drug delivery. Vol. 2. 2014: CRC Press.
  3. Ahmad, M.Z., et al., Metallic nanoparticles: technology overview & drug delivery applications in oncology. Expert opinion on drug delivery, 2010. 7(8): p. 927-942.
  4. Kreyling, W.G., M. Semmler-Behnke, and Q. Chaudhry, A complementary definition of nanomaterial. Nano today, 2010. 5(3): p. 165-168.
  5. Martirosyan, A., A. Bazes, and Y.-J. Schneider, In vitro toxicity assessment of silver nanoparticles in the presence of phenolic compounds–preventive agents against the harmful effect? Nanotoxicology, 2014. 8(5): p. 573-582.
  6. Shahverdi, A.R., et al., Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomedicine: Nanotechnology, Biology and Medicine, 2007. 3(2): p. 168-171.
  7. Wong, K., Silver nanoparticles in medicine: is the panacea here. Nanomedicine: Nanotechnology, Biology and Medicine, 2012. 8(6): p. 935-940.
  8. Nagal, A. and R.K. Singlab, Nanoparticles in different delivery systems: a brief review. organ, 2013. 1: p. 4.
  9. Dabney-Smith, K., et al., Severe esophagitis healed in less than a week with intravenous pantoprazole. Journal of clinical gastroenterology, 2003. 36(1): p. 78-79.
  10. Thompson, W., et al., Effect of a proton pump inhibitor deprescribing guideline on drug usage and costs in long-term care. Journal of the American Medical Directors Association, 2016. 17(7): p. 673. e1-673. e4.
  11. Rethy, B., et al., Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens. Planta medica, 2007. 73(01): p. 41-48.
  12. Srivastava, S., S. Srivastava, and K. Halwe, New coumarins and limonoids of Ruta graveolens. Fitoterapia (Milano), 1998. 69(1): p. 80-81.
  13. Nabhan, G.P. and G.P. Nabhan, Urban Growers and Rare Fruits. Food from the Radical Center, 2018: p. 123-133.